The resistive and elastic work of breathing during exercise in patients with chronic heart failure

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The resistive and elastic work of breathing during exercise in patients with chronic heart failure.

Patients with heart failure (HF) display numerous derangements in ventilatory function, which together serve to increase the work of breathing (W(b)) during exercise. However, the extent to which the resistive and elastic properties of the respiratory system contribute to the higher W(b) in these patients is unknown. We quantified the resistive and elastic W(b) in patients with stable HF (n = 9...

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Sex differences in the resistive and elastic work of breathing during exercise in endurance-trained athletes.

It is not known whether the high total work of breathing (WOB) in exercising women is higher due to differences in the resistive or elastic WOB. Accordingly, the purpose of this study was to determine which factors contribute to the higher total WOB during exercise in women. We performed a comprehensive analysis of previous data from 16 endurance-trained subjects (8 men and 8 women) that underw...

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Acetazolamide and inhaled carbon dioxide reduce periodic breathing during exercise in patients with chronic heart failure.

BACKGROUND Periodic breathing (PB) during sleep and exercise in heart failure (HF) is related to respiratory acid-base status, CO2 chemosensitivity, and temporal dynamics of CO2 and O2 sensing. We studied inhaled CO2 and acetazolamide to alter these factors and reduce PB. METHODS AND RESULTS We measured expired and arterial gases and PB amplitude and duration in 20 HF patients during exercise...

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Dysanapsis and the Resistive Work of Breathing during Exercise in 1 Healthy Men and Women

Sex differences in respiratory mechanics 1 DYSANAPSIS AND THE RESISTIVE WORK OF BREATHING DURING EXERCISE IN 1 HEALTHY MEN AND WOMEN 2 Paolo B. Dominelli, Yannick Molgat-Seon, Derek Bingham, Philippa M. Swartz, Jeremy D. 3 Road, Glen E. Foster and A. William Sheel 4 School of Kinesiology, University of British Columbia, Vancouver, BC, Canada 5 Department of Statistics and Actuarial Science, Sim...

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Dysanapsis and the resistive work of breathing during exercise in healthy men and women.

We asked if the higher work of breathing (Wb) during exercise in women compared with men is explained by biological sex. We created a statistical model that accounts for both the viscoelastic and the resistive components of the total Wb and independently compares the effects of biological sex. We applied the model to esophageal pressure-derived Wb values obtained during an incremental cycle tes...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2011

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00125011